Baby Allergies
Genetics can explain if you are allergic to pollen or certain foods?
Baby Allergies
Models of white blood cells and determine how genetically determined HLA DQ and DR genes have been identified with an increased risk of allergy to pollen, dust, latex and food. The fascinating aspect of this story is that there is an advantage of knowing your HLA DR and DQ type when evaluating the risk of allergies to pollen and food allergies or againstReactions.
Baby Allergies
Genetics of food allergy reactions and
Baby Allergies
As I explain in detail in my article on the genetics of gluten intolerance, we have all the proteins on the surface of our cells that are genetically determined. These models are easily identified by examining the cells of blood or mouth swab. Specific model with an increased risk of autoimmune disease, gluten intolerance and celiac disease associated Disease.
HLA DQ gene and celiac disease or gluten intolerance
HLA DQ2 is present in over 90% of people who have celiac disease, while in most other HLADQ8, but not all people with celiac disease were found DQ2 and / or DQ8.
DQ and DR genetic patterns of food allergies and sensitivities to pollen or online?
Now it seems some models of DQ and DR are associated with pollen and food> Allergies well. From the Food Doc, I continue to look to literature for further information on food allergies and intolerances genetic. My research brought me some interesting articles in the unusual range of oral allergy syndrome (OAS). The relationship between seasonal and perennial nasal allergies and food allergies is certainly well established, but they are generally known by most doctors and patients. It seems that some of us needavoid eating certain foods, hay fever or allergies when we, especially during the hay fever season. This problem seems to be inherited.
Search for genetic association with food allergy and pollen records
Boehncke, et al. reported by the University of Frankfurt in 1998, that certain types of white blood cells known HLA class II genotypes or HLA DQ and DR genetic patterns were found more frequently in people with certain pollensFood allergies. HLA-DQB1 * 0301 is more allergic to grass pollen. Ones associated with HLA-DRB1 * 08, an inherited disease of white blood cell protein models with an allergy to grass pollen, six times the risk of peanut allergy increased. Those who inherit the HLA DRB1 * 12 white blood cells are 13 times higher risk of allergy to carrots.
Tree to tree pollen allergy seems to be birch pollenPires
Allergy to birch pollen, hazelnut associated HLA-DRB1 * 01, DQA1 * 0101 and DQB1 * 0501 is associated. Hazelnuts, almonds, walnuts and the apple of most common food allergies associated with birch pollen. Allergies to these foods often associated with birch pollen in other studies.
Weed allergies and food intolerance associated
In 2004, Wang et al. published in China that has inherited the white blood cellsCell type, DQA1 * 0302 is more people with Artemisia pollen allergic rhinitis, hay fever are found in grass or mugwort wormwood. Sagebrush allergies multiple food allergies, including apples, celery, hazelnut, pistachio, salad, almonds, peanuts and carrot attached.
Where to find the genetic testing
There are three commercial laboratories that I am aware that giving full DQ'm HLA typing. This is Quest laboratories, the laboratory BonfilsDenver and Enterolab. Bonfils is Enterolab genetic testing. Enterolab offers tests on samples of cells from a Q-tip Q-tip to run into his mouth. The test can be obtained directly from Enterolab without a prescription from a doctor if you are not covered by insurance. However, it is very reasonable from the point of genetic testing for $ 149. Bonfils non-DQ typing of cells derived from blood samples sent to other laboratories.
The future of genetic testing in the pollen andFood Allergies
In the future, these tests should be useful for evaluating suspected allergies, intolerances and allergies from pollen. In the meantime, those of us interested in this story interesting to look forward to further research in this exciting field. Dr. Fine, the founder of the reasons was associated with HLA DQ Enterolab published microscopic colitis. He found that microscopic changes in the colon or large intestinesimilar if not identical to what you see in the small intestine in celiac disease. Several articles of the document now working on a gluten-free diet for many people with microscopic colitis, lymphocytic and collagen. It also helps a lot to Crohn's disease and ulcerative colitis.
The finding of intraepithelial lymphocytosis in the distal small intestine (ileum) is associated with an increased incidence of celiac disease in the proximal small intestine. Now, in addition to the plot, areIn this article the connection of certain white blood cells, proteins, genes, models for pollen allergy and food allergy cross-reactions, which are generally accepted, but rarely followed up clinically. Oral allergy syndrome (OAS), also called "syndrome, burning of mouth ", occurs in many people, but the symptoms are often not diagnosed. include burning, pain and / or itching of the mouth or throat, with or without edema, which occurs almost immediately after eating certain foods. Foods that are too often these reactions with pollen, dust or allergy to latex.
Unusual combination of burning mouth and pollen allergies or reactions to food
This unusual combination of trees, grass and grass pollen, dust mites and latex allergy reactions to foods, but there are also documented in the medical literature, often unrecognized by physicians or patients. The literature contains numerous reports of food OAS> The reactions of allergy or intolerance to certain pollens, dust, mold, or allergic to latex. One of the best examples is the allergy to ragweed pollen. There is a high risk of food allergy or intolerance to certain foods. These foods are part of the family Cucurbitaceae (melons and cucumber) and banana. On the other hand, allergy to birch pollen is associated with a sensitivity to many foods. The list includes foods rosaceaFamily (apples, pears), the family of nuts (hazelnuts, almonds, walnuts), potatoes and carrots. Reactions are classic allergic reactions like skin rashes (atopic dermatitis), urticaria, wheezing (asthma), runny nose (allergic rhinitis), and symptoms of burning in the mouth of the OAS and other symptoms of food intolerance.
If you have a food allergy, intolerance or sensitivity suspect Receive an expertise
People who suspect a food allergy or food intoleranceare invited to check the connection of pollen-food and a proper evaluation of food allergies, intolerances and sensitivities. Food sensitivity includes sensitivity to gluten and cow's milk (casein) the sensitivity of the protein. Food intolerance is lactose intolerance. Food allergies are separate and distinct from both food sensitivities or intolerances.
Let us first consider genetic testing or ask your doctor to see
This new informationthe combination of the tendency of the blood proteins of white blood cells, HLA DQ type, suggests that we should consider genetic testing. After appropriate assessment,
Get a score of basic symptoms and diet food diary symptoms begin
I invite everyone to a score of basic symptoms for the development. A detailed food diary of symptoms before a process of elimination diet is also very useful. An elimination diet, food lectins important (dairy products, cereals, legumes and Solanaceae) includesand all foods, pollen from the list that you are allergic before accepting the diagnosis of IBS, recommended fibromyalgia, neuropathy, or headaches and unexplained chronic fatigue. All the symptoms are not easy to explain or to be established with other diagnoses and treatments is considered to be improved due to a reaction to food components, until proven otherwise.
Selected Bibliography
Boehncke, et al. Clin Exp Allergy. April 1998, 28 (4) :434-41.
Fine KD et al. Am JGastroenterol. August 2000, 95 (8) :1974-82.
Wang et al. Otolaryngol Head Neck Surg February, 130 (2): 192-197.
